endTB: finding shorter, less toxic, and more effective treatments for MDR-TB
The endTB project aims to find shorter, less toxic and more effective treatments for ‘multidrug-resistant TB’ (MDR-TB) through: 1) access to new drugs, 2) two clinical trials, and 3) advocacy at national and global levels.
The groundbreaking endTB clinical trial results were just published, where a personalized medicine approach highlights the benefits of a new shorter treatment strategy for extensively drug-resistant tuberculosis.
Read the new publication and over 40 research resources, publications, and protocol documents from the endTB project.
Noma, a neglected disease
Noma, also known as cancrum oris, is a rapidly progressing life-threatening infection that affects the mouth and face. Noma is preventable and easy to treat if addressed in the early reversible stages, but most often deadly if untreated. The disease most commonly affects children who are chronically malnourished or whose immune systems are otherwise compromised. Noma affects an estimated 140,000 children annually. Noma was added to the WHO's list of Neglected Tropical Diseases in 2023.
MSF is working to discover more about noma. This collection highlights MSF's mixed methods research on treatment outcomes, burden of disease, attitudes towards the disease and other aspects of noma.
Safe abortion care at MSF
Unsafe abortion is one of the main causes of maternal death, and the only one that is completely preventable. Yet over 30 million unsafe abortions occur each year, leading to at least 28,000 deaths and millions of serious complications—nearly all in low- and middle-income countries. MSF teams see these tragic consequences first-hand, treating thousands of patients every year with severe, potentially life-threatening effects from unsafe abortion.
To mark International Safe Abortion Awareness Day (28 September 2023) this Collection presents highlights of MSF’s work on providing SAC as a way to reduce maternal death and injury. By re-assessing and reshaping how our projects deliver SAC in fragile and conflict-affected settings, we have been able to significantly expand services not only in those contexts but across MSF projects globally. In parallel we also conducted in-depth studies of abortion-related dynamics in several complex settings, especially among women who experienced severe complications. Collectively these findings are helping to identify gaps in service delivery and inform operational decision-making. And in a shift accelerated by the Covid-19 pandemic, we are increasingly working towards and advocating for more community-led, self-managed SAC.
