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TB Research Dissemination Workshop 2022 | Collections | MSF Science Portal
TB Research Dissemination Workshop 2022

TB Research Dissemination Workshop 2022

On June 30th-July 1, 2022 the research team at Epicentre in Mbarara, Uganda held a two-day workshop about their recent work to address gaps in tuberculosis diagnostics and therapeutics in low-income countries. Sessions included:


• Landscape of TB disease in Uganda: research gaps

• New diagnostic tools and algorithms in adults

• New diagnostic tools and algorithms in children

• Approaches to increasing pediatric TB detection and reducing disease burden

• TB chemotherapeutics

• Perspectives and challenges in TB


To catch up on the presentations, you can view the abstracts through the link below.

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Antibiotic resistance, conflict and the Middle East
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International Safe Abortion Day 2022

International Safe Abortion Day 2022
Unsafe abortion is a leading cause of maternal death, and the only one that is completely preventable. Yet over 30 million unsafe abortions occur each year, leading to at least 28,000 deaths and millions of serious complications—nearly all in low- and middle-income countries. MSF teams see these tragic consequences first-hand, treating thousands of patients every year with severe, potentially life-threatening effects from unsafe abortion. So in 2016 we launched a program to systematically implement safe abortion care (SAC), starting with ten pilot sites and then applying the lessons learned to scale up at projects across the globe. This Collection presents highlights of these efforts. Since our first publication on the need to provide SAC as a way of reducing maternal death and injury, several studies assessed the role of unsafe abortion in driving this suffering in specific contexts. Others described internal obstacles to providing SAC, operational solutions developed, and outcomes achieved. And we advocated for shifting towards community-led and self-managed SAC, particularly given new obstacles that emerged during the Covid-19 pandemic.
MSF Paediatric Days 2024 abstracts

MSF Paediatric Days 2024 abstracts
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On 3-4 May in Nairobi, Kenya, MSF gathered staff from our projects with experts from academia, clinical practice and the non-governmental sector to consider key issues in humanitarian paediatrics. These included: Vaccination and vaccine-preventable diseases: Amid post-Covid-19 global setbacks in child vaccination coverage, sessions spotlighted recent increases in vaccine-preventable disease outbreaks, potential new vaccination strategies and emergency responses, and MSF’s role in vaccine advocacy and catch-up campaigns. Nutrition: Talks covered the nexus of nutrition with other key conference topics, the latest malnutrition guidance and tools, and MSF’s priorities in nutritional care. Paediatric HIV: With half of all HIV-positive children globally not receiving antiretroviral therapy, presenters reviewed the latest paediatric testing/treatment recommendations and discussed barriers and potential solutions to implementation, nutritional challenges in children with HIV, and systems strengthening for preventing and monitoring paediatric HIV. Click below to read the abstracts. And stay tuned for more conference content, coming soon.
Conference Material
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Video

TB research dissemination workshop: key takeaways

Boum Y II
2022-07-01 • TB Research Dissemination Workshop, Epicentre Uganda
2022-07-01 • TB Research Dissemination Workshop, Epicentre Uganda
Conference Material
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Abstract

Acceptability and feasibility of a household child-contact investigation and preventive therapy management in Cameroon and Uganda

Vasiliu A
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
The CONTACT study (Cameroon, Uganda) is a cluster-randomized trial evaluating a community intervention for tuberculosis contact investigation and tuberculosis preventive treatment manage...
Conference Material
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Abstract

COVID-19 in HIV-positive patients investigated for tuberculosis in the context of the FujiLAM study

Taremwa IM
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
People with immunosuppression may be particularly vulnerable to SARS-CoV-2 and some symptoms of infection by SARS-CoV-2 and TB are similar. Dual infection with both TB and...
Conference Material
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Abstract

Evaluation of centrifuge-free stool processing methods combined with Xpert MTB/RIF ultra for diagnosis of intrathoracic paediatric TB

Kaitano R
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
There is a growing interest for the use of stool samples as an alternative to respiratory samples for the diagnosis of intrathoracic TB in children unable to produce sputu...
Conference Material
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Abstract

Feasibility of implementing the FujiLAM assay and acceptability by health workers and patients

Muyindike WR
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
The novel urine-based FujiLAM test identifies tuberculosis in HIV-positive patients but may be challenging to use as a point-of-care (POC) test.

OBJECTIVES
We...
Conference Material
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Abstract

Impact of systematic TB detection using Xpert Ultra on nasopharyngeal aspirates and stool samples on mortality in children with severe pneumonia

Mwanga-Amumpaire J
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
In children with severe pneumonia, TB is usually considered only in case of prolonged symptoms or antibiotic failure, leading to missed or delayed TB diagnosis. Systematic...
Conference Material
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Abstract

Tuberculosis diagnostic accuracy of stool xpert MTB/RIF and urine alereLAM in vulnerable children

Nampijja D
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
Non-sputum-based diagnostic approaches are crucial in children at high risk of disseminated tuberculosis (TB) who cannot expectorate sputum. We evaluated the diagnostic ac...
Conference Material
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Abstract

Diagnostic performance of the novel FujiLAM assay to detect tuberculosis in HIV-positive patients

Huerga H
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
The novel urine-based point-of-care FujiLAM assay is a promising tool for tuberculosis (TB) diagnosis. We prospectively assessed the diagnostic accuracy of FujiLAM and we ...
Conference Material
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Abstract

Increased child contact investigation and tuberculosis preventive treatment management through a community-based intervention in Cameroon and Uganda: Results of the contact cluster randomized trial

Atwine D
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
CONTEXT
In tuberculosis (TB) endemic countries, the screening and management of household contacts remains low including the uptake of TB preventive treatment (TPT). One of the chall...
Conference Material
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Abstract

Systematic or test-guided treatment for tuberculosis in HIV-infected adults

Muzoora C
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
In regions with high burdens of tuberculosis and human immunodeficiency virus (HIV), many HIV-infected adults begin antiretroviral therapy (ART) when they are already seve...