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ASTMH Annual Meeting 2024 | Collections | MSF Science Portal

The American Society of Tropical Medicine & Hygiene (ASTMH) Annual Meeting is an international forum for the exchange of scientific and clinical advances in tropical medicine, hygiene and global health. The scientific content this year is 53% microbe focused, 15% clinically focused, 13% vector focused, 13% globally focused, and 6% intervention focused.

MSF and Epicentre are presenting on access and other challenges for children with visceral and cutaneous leishmaniasis, hurdles in malaria diagnostic testing, and ensuring equitable access to healthcare in conversations about financial sustainability.

This collection features research authored by the presenters and other topics highlighted at ASTMH.

Collection Content

Journal Article
|
Letter

Mpox: Neglect has led to a more dangerous virus now spreading across borders, harming and killing people. Leaders must take action to stop mpox now

McNab C, Torreele E, Alakija A, Aluso A, Cárdenas M,  et al.
2024-10-17 • PLOS Global Public Health
2024-10-17 • PLOS Global Public Health
Journal Article
|
Research

The economic burden of visceral leishmaniasis and barriers to accessing healthcare in Tigray, North Ethiopia: A field based study

Tessema SB, Hagos T, Kehasy G, Paintain L, Adera C,  et al.
2024-10-15 • PLOS Neglected Tropical Diseases
2024-10-15 • PLOS Neglected Tropical Diseases

BACKGROUND

Visceral leishmaniasis (VL) is an important public health problem, which mainly affects the poor rural dwelling communities in Low- and Middle-Income...

Journal Article
|
Research

Field evaluation of validity and feasibility of Pan-Lassa rapid diagnostic test for Lassa fever in Abakaliki, Nigeria: a prospective diagnostic accuracy study

Elsinga J, Sunyoto T, di Stefano L, Giorgetti PF, Kyi HA,  et al.
2024-09-01 • Lancet Infectious Diseases
2024-09-01 • Lancet Infectious Diseases
BACKGROUND
Lassa fever is a viral haemorrhagic fever with few options for diagnosis and treatment; it is also under-researched with knowledge gaps on its epidemiology. A point-of-car...
Journal Article
|
Research

A Pan Plasmodium lateral flow recombinase polymerase amplification assay for monitoring malaria parasites in vectors and human populations

Higgins M, Kristan M, Collins EL, Messenger LA, Dombrowski JG,  et al.
2024-08-30 • Scientific Reports
2024-08-30 • Scientific Reports

Robust diagnostic tools and surveillance are crucial for malaria control and elimination efforts. Malaria c...

Conference Material
|
Poster

Descriptions of a paediatric visceral leishmaniasis cohort and their outcomes in Upper Nile State, South Sudan

Litster M, Sangma M, Kihara M, Nanclares C, de Bartolome Gisbert F,  et al.
2024-05-03 • MSF Paediatric Days 2024
2024-05-03 • MSF Paediatric Days 2024
Journal Article
|
Protocol

Host, parasite and drug determinants of clinical outcomes following treatment of visceral leishmaniasis: a protocol for individual participant data meta-analysis

Kumar R, Dahal P, Singh-Phulgenda S, Siddiqui NA, Munir A,  et al.
2023-10-28 • BMJ Open
2023-10-28 • BMJ Open
INTRODUCTION
Visceral leishmaniasis (VL) is a parasitic disease with an estimated 30 000 new cases occurring annually. There is an observed variation in the efficacy of the current f...
Journal Article
|
Research

Proportion of paediatric admissions with any stage of noma at the Anka General Hospital, northwest Nigeria

Farley ES, Karinja MN, Lawal AM, Olaleye M, Muhammad S,  et al.
2023-10-27 • PLOS Neglected Tropical Diseases
2023-10-27 • PLOS Neglected Tropical Diseases
INTRODUCTION
Noma is a rapidly spreading infection of the oral cavity which mainly affects young children. Without early treatment, it can have a high mortality rate. Simple gingivit...
Journal Article
|
Research

Evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria and prevalence of pfhrp2/3 deletions in Aweil, South Sudan

Lynch E, Jensen TO, Assao B, Chihana ML, Turuho T,  et al.
2022-09-09 • Malaria Journal
2022-09-09 • Malaria Journal
BACKGROUND
Rapid diagnostic tests (RDT) for malaria are the primary tool for malaria diagnosis in sub-Saharan Africa but the utility of the most commonly used histidine-rich protein ...
Journal Article
|
Review

Visceral leishmaniasis in pregnancy and vertical transmission: A systematic literature review on the therapeutic orphans

Dahal P, Singh-Phulgenda S, Maguire BJ, Harriss E, Ritmeijer KKD,  et al.
2021-08-10 • PLOS Neglected Tropical Diseases
2021-08-10 • PLOS Neglected Tropical Diseases
BACKGROUND
Reports on the occurrence and outcome of Visceral Leishmaniasis (VL) in pregnant women is rare in published literature. The occurrence of VL in pregnancy is not systematic...
Journal Article
|
Research

Field safety and effectiveness of new visceral leishmaniasis treatment regimens within public health facilities in Bihar, India

Goyal V, Mahajan R, Pandey K, Singh SN, Singh RS,  et al.
2018-10-22 • PLOS Neglected Tropical Diseases
2018-10-22 • PLOS Neglected Tropical Diseases
BACKGROUND
In 2010, WHO recommended the use of new short-course treatment regimens in kala-azar elimination efforts for the Indian subcontinent. Although phase 3 studies have shown e...

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Noma

Noma

Noma, also known as cancrum oris, is a rapidly progressing life-threatening infection that affects the mouth and face. Noma is preventable and easy to treat if addressed in the early reversible stages, but most often deadly if untreated. The disease most commonly affects children who are chronically malnourished or whose immune systems are otherwise compromised. Noma affects an estimated 140,000 children annually. Noma was added to the WHO's list of Neglected Tropical Diseases in 2023. 


MSF is working to discover more about noma. This collection highlights MSF's mixed methods research on treatment outcomes, burden of disease, attitudes towards the disease and other aspects of noma.


For more information on MSF's work on noma, you can also visit https://noma.msf.org/.

Combatting antimicrobial resistance

Combatting antimicrobial resistance

Antimicrobial resistance is a growing public health crisis, especially in countries with fragile health systems, population displacement or ongoing conflict. In 2019 antibiotic-resistant bacteria directly caused an estimated 1.27 million deaths, and contributed to 4.95 million deaths, tolls that will continue to increase if no effective action is taken.


MSF’s approach to combatting antimicrobial resistance combines three pillars: infection prevention and control, microbiology and surveillance, and rational use of antibiotics via antibiotic stewardship. Several studies characterize patterns and prevalence of antibiotic resistance among MSF patients, from civilians wounded in Middle East conflicts to hospitalized neonates in Central African Republic and Haiti. New technologies developed by MSF and partners are expanding local capacity for rapid, accurate laboratory diagnosis of infections, so that clinicians can prescribe the right antibiotic for each patient. Other work assesses the practices and challenges related to optimizing rational antibiotic use within health facilities and communities.

If you're interested in learning more about MSF's work in antimicrobial resistance, view the full list of MSF's publications on the topic.

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ASTMH Annual Meeting 2024

ASTMH Annual Meeting 2024