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Costs, cost-effectiveness, and financing of tuberculosis treatment | Collections | MSF Science Portal
Costs, cost-effectiveness, and financing of tuberculosis treatment

Costs, cost-effectiveness, and financing of tuberculosis treatment

Tuberculosis (TB) is the world's deadliest infectious disease, and the leading killer of people with HIV. TB is curable, but it can be difficult to diagnose and tough to treat, especially for increasingly prevalent drug-resistant TB. In 2023, 22,700 people started TB treatment in MSF programs. Understanding the costs and cost-effectiveness associated with TB treatment and innovations, ranging from TB diagnostics and medications to TB care models, can help to plan resource needs and allocate resources effectively. Analyzing financing mechanisms can support developing sustainable funding models for TB control.

This collection spotlights articles by MSF and collaborators to analyze and document the costs of care, particularly diagnostics and medications.

Collection Content

Journal Article
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Research

Trends in the availability and prices of quality-assured tuberculosis drugs: a systematic analysis of Global Drug Facility Product Catalogs from 2001 to 2024

Kohler S, Achar J, Mulder C, Sitali N, Paul N
2024-06-25 • Globalization and Health
2024-06-25 • Globalization and Health
BACKGROUND
The Global Drug Facility (GDF) of the Stop TB Partnership was launched in 2001 with the goal of increasing access to quality-assured tuberculosis (TB) drugs and products. ...
Journal Article
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Research

Costs and import costs of past, present, and future TB drug regimens: a case study for Karakalpakstan, Uzbekistan

Kohler S, Sitali N, Achar J, Paul N
2022-11-23 • Journal of Public Health
2022-11-23 • Journal of Public Health
BACKGROUND
Tuberculosis (TB) drugs and their import are costly. We assessed how shorter TB drug regimens, which were non-inferior or superior in recent TB trials, can affect the cost...
Journal Article
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Research

The contribution of drug import to the cost of tuberculosis treatment: A cost analysis of longer, shorter, and short drug regimens for Karakalpakstan, Uzbekistan

Kohler S, Sitali N, Achar J, Paul N
2022-08-03 • PLOS Global Public Health
2022-08-03 • PLOS Global Public Health

Tuberculosis (TB) programs depend on a continuous supply of large amounts of high-quality TB drugs. When TB programs procure TB drugs from international suppliers, such as the Global ...

Journal Article
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Research

Programme costs of longer and shorter tuberculosis drug regimens and drug import: a modelling study for Karakalpakstan, Uzbekistan

Kohler S, Sitali N, Achar J, Paul N
2022-03-21 • ERJ open research
2022-03-21 • ERJ open research
BACKGROUND
The introduction of new and often shorter tuberculosis (TB) drug regimens affects the cost of TB programmes.

METHODS
We modelled drug purchase and import cost...
Journal Article
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Research

A framework for assessing import costs of medical supplies and results for a tuberculosis program in Karakalpakstan, Uzbekistan

Kohler S, Sitali N, Paul N
2021-08-25 • Health Data Science
2021-08-25 • Health Data Science

BACKGROUND

Import of medical supplies is common, but limited knowledge about import costs and their structure introduces uncertainty to budget planning, cost ma...

Journal Article
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Research

Health system support and health system strengthening: two key facilitators to the implementation of ambulatory tuberculosis treatment in Uzbekistan

Kohler S, Asadov DA, Bründer A, Healy S, Khamraev AK,  et al.
2016-07-12 • Health Economics Review
2016-07-12 • Health Economics Review

Uzbekistan inherited a hospital-based health system from the Soviet Union. We explore the health system-related challenges faced during the scale-up of ambulatory (outpatient) treatme...

Journal Article
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Research

Ambulatory tuberculosis treatment in post-Semashko health care systems needs supportive financing mechanisms

Kohler S, Asadov D, Brunder A, Healy S, Khamraev AK,  et al.
2014-12-01 • International Journal of Tuberculosis and Lung Disease
2014-12-01 • International Journal of Tuberculosis and Lung Disease
The tuberculosis (TB) control strategy in the Republic of Karakalpakstan, Uzbekistan, is being changed to decentralised out-patient care for most TB patients by the Government of Uzbekis...

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World Hand Hygiene Day 2023

World Hand Hygiene Day 2023
"Clean hands, safe care" is the theme of this year's World Hand Hygiene Day. At MSF, we know that Hand Hygiene is the simplest and best way to prevent the transmission of infections in our facilities. This collection features some lessons learned about hand hygiene and infection, prevention, & control (IPC) in MSF projects, especially in resource-constrained environments in the Sahel, and in the era of COVID-19.
International Safe Abortion Day 2022

International Safe Abortion Day 2022
Unsafe abortion is a leading cause of maternal death, and the only one that is completely preventable. Yet over 30 million unsafe abortions occur each year, leading to at least 28,000 deaths and millions of serious complications—nearly all in low- and middle-income countries. MSF teams see these tragic consequences first-hand, treating thousands of patients every year with severe, potentially life-threatening effects from unsafe abortion. So in 2016 we launched a program to systematically implement safe abortion care (SAC), starting with ten pilot sites and then applying the lessons learned to scale up at projects across the globe. This Collection presents highlights of these efforts. Since our first publication on the need to provide SAC as a way of reducing maternal death and injury, several studies assessed the role of unsafe abortion in driving this suffering in specific contexts. Others described internal obstacles to providing SAC, operational solutions developed, and outcomes achieved. And we advocated for shifting towards community-led and self-managed SAC, particularly given new obstacles that emerged during the Covid-19 pandemic.
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Advancing Research to Improve NTD Treatments in Children by Saschveen Singh

Dr. Saschveen Singh is a tropical infectious disease advisor for MSF. Read more of MSF's recent work on neglected tropical diseases in pediatric populations, and of Dr. Singh's work at MSF.

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