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Showing 1 - 20 of 30 Items
Showing 1 - 20 of 30 Items
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Protecting the safe water chain in refugee camps: An exploratory study of water handling practices, chlorine decay, and household water safety in South Sudan, Jordan, and Rwanda

Ali SI, De Santi M, Monette G, Khan UT, Fesselet JF,  et al.
2024-12-03 • Journal of the American Medical Association (JAMA)
2024-12-03 • Journal of the American Medical Association (JAMA)

In refugee and internally displaced person settlements, hygienic water handling and free residual chlorine (FRC) are crucial for protecting water against recontamination after distrib...

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The prevalence of mental health problems in Rwandan and Burundese refugee camps

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Carriage of third-generation cephalosporin-resistant and carbapenem-resistant Enterobacterales among children in sub-Saharan Africa: a systematic review and meta-analysis

Ruef M, Emonet S, Merglen A, Dewez JE, Obama BM,  et al.
2024-03-11 • eClinicalMedicine
2024-03-11 • eClinicalMedicine
BACKGROUND
The increasing resistance of Enterobacterales to third-generation cephalosporins and carbapenems in sub-Saharan Africa (SSA) is a major public health concern. We did a sys...

Antimicrobial resistance in Enterobacterales infections among children in sub-Saharan Africa: a systematic review and meta-analysis

Kowalski M, Minka Obama B, Catho G, Dewez JE, Merglen A,  et al.
2024-03-08 • eClinicalMedicine
2024-03-08 • eClinicalMedicine
BACKGROUND
The burden of antimicrobial resistance (AMR) has been estimated to be the highest in sub-Saharan Africa (SSA). The current study estimated the proportion of drug-resistant...

Définition d'un jeu universel de critères de décision de base pour les essais cliniques sur les morsures de serpent

Abouyannis M, Esmail H, Hamaluba M, Ngama M, Mwangudzah H,  et al.
2023-02-01 • Médecine tropicale et santé internationale
2023-02-01 • Médecine tropicale et santé internationale
CONTEXTE
Les essais cliniques sur les morsures de serpent ont souvent utilisé des critères de décision hétérogènes qui demandent à être standardisés.

MÉTHODE
Un groupe d...

High prevalence of lipoatrophy among patients on stavudine-containing first-line antiretroviral therapy regimens in Rwanda

van Griensven J, De Naeyer L, Mushi T, Ubarijoro S, Gashumba D,  et al.
2007-08-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2007-08-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
This study was conducted among individuals placed on WHO-recommended first-line antiretroviral therapy (ART) at two urban health centres in Kigali, Rwanda, in order to determine (a) the ...

African medical educators and anatomy teachers' perceptions and acceptance of the anatomage table as an edTech and innovation: a qualitative study

Owolabi JO, Ojiambo R, Seifu D, Nishimwe A, Masimbi O,  et al.
2022-06-06 • Advances in Medical Education and Practice
2022-06-06 • Advances in Medical Education and Practice
BACKGROUND
This article presents a qualitative study of African anatomists and anatomy teachers on the Anatomage Table-a modern medical education technology and innovation, as an ind...

Evaluating process and clinical outcomes of a primary care mental health integration project in rural Rwanda: a prospective mixed-methods protocol

Smith SL, Misago CN, Osrow RA, Franke MF, Iyamuremye JD,  et al.
2017-02-01 • BMJ Open
2017-02-01 • BMJ Open
Integrating mental healthcare into primary care can reduce the global burden of mental disorders. Yet data on the effective implementation of real-world task-shared mental health program...

Weight loss after the first year of stavudine-containing antiretroviral therapy and its association with lipoatrophy, virological failure, adherence and CD4 counts at primary health care level in Kigali, Rwanda

van Griensven J, Zachariah R, Mugabo J, Reid AJ
2010-12-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2010-12-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
This study was conducted among 609 adults on stavudine-based antiretroviral treatment (ART) for at least one year at health center level in Kigali, Rwanda to (a) determine the proportion...

Making progress towards food security: evidence from an intervention in three rural districts of Rwanda

Nsabuwera V, Hedt-Gauthier BL, Khogali MA, Edginton ME, Hinderaker SG,  et al.
2015-08-06 • Public Health Nutrition
2015-08-06 • Public Health Nutrition
OBJECTIVE
Determining interventions to address food insecurity and poverty, as well as setting targets to be achieved in a specific time period have been a persistent challenge for d...

Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis

Zwang J, Olliaro PL, Barennes H, Bonnet MMB, Brasseur P,  et al.
2009-08-23 • Malaria Journal
2009-08-23 • Malaria Journal
BACKGROUND: Artesunate and amodiaquine (AS&AQ) is at present the world's second most widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the efficacy of...

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

Dondorp AM, Fanello CI, Hendriksen IC, Gomes E, Seni A,  et al.
2010-11-08 • Lancet
2010-11-08 • Lancet
Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established treatment of choice...

Evidence-based chlorination targets for household water safety in humanitarian settings: Recommendations from a multi-site study in refugee camps in South Sudan, Jordan, and Rwanda

Ali SS, Fesselet JF
2020-11-16 • Water Research
2020-11-16 • Water Research
The current Sphere guideline for water chlorination in humanitarian emergencies fails to reliably ensure household water safety in refugee camps. We investigated post-distribution chlori...

Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria

Van Malderen C, Van Geertruyden JP, Machevo S, Gonzalez R, Bassat Q,  et al.
2012-04-30 • Malaria Journal
2012-04-30 • Malaria Journal
BACKGROUND
Malaria is a leading cause of mortality, particularly in sub-Saharan African children. Prompt and efficacious treatment is important as patients may progress within a few ...

Stavudine- and nevirapine-related drug toxicity while on generic fixed-dose antiretroviral treatment: incidence, timing and risk factors in a three-year cohort in Kigali, Rwanda

van Griensven J, Zachariah R, Rasschaert F, Mugabo J, Atté EF,  et al.
2010-02-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2010-02-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
This cohort study was conducted to report on the incidence, timing and risk factors for stavudine (d4T)- and nevirapine (NVP)-related severe drug toxicity (requiring substitution) with a...

Correcting mortality for loss to follow-up: a nomogram applied to antiretroviral treatment programmes in sub-Saharan Africa

Egger M, Sidle J, Weigel R, Geng EH, Fox MP,  et al.
2011-01-01 • PLOS Medicine
2011-01-01 • PLOS Medicine
The World Health Organization estimates that in sub-Saharan Africa about 4 million HIV-infected patients had started antiretroviral therapy (ART) by the end of 2008. Loss of patients to ...

A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995)

Kerneis S, Guerin PJ, von Seidlein L, Legros D, Grais RF
2009-02-13 • PLOS One
2009-02-13 • PLOS One
BACKGROUND: Shigella dysenteriae type 1 (Sd1) is a cause of major dysentery outbreaks, particularly among children and displaced populations in tropical countries. Although outbreaks con...
de Jong J, Scholte WF, Koeter MW, Hart AA
2000-09-01 • Acta Psychiatrica Scandinavica
2000-09-01 • Acta Psychiatrica Scandinavica
OBJECTIVE
We examined the prevalence of mental health problems in refugees living in camps that emerged in Tanzania during the Rwanda crisis that started in 1994.

METHOD

Paediatric pharmacovigilance: use of pharmacovigilance data mining algorithms for signal detection in a safety dataset of a paediatric clinical study conducted in seven african countries

Kajungu DK, Erhart A, Talisuna AO, Bassat Q, Karema C,  et al.
2014-05-01 • PLOS One
2014-05-01 • PLOS One
Pharmacovigilance programmes monitor and help ensuring the safe use of medicines which is critical to the success of public health programmes. The commonest method used for discovering p...

Complex interactions between malaria and malnutrition: a systematic literature review

Das D, Grais RF, Okiro EA, Stepniewska K, Mansoor R,  et al.
2018-10-29 • BMC Medicine
2018-10-29 • BMC Medicine
Despite substantial improvement in the control of malaria and decreased prevalence of malnutrition over the past two decades, both conditions remain heavy burdens that cause hundreds of ...

Caring for patients with surgically resectable cancers: experience from a specialised centre in rural Rwanda

Mubiligi JM, Hedt-Gauthier BL, Mpunga T, Tapela N, Okao P,  et al.
2014-06-21 • Public Health Action
2014-06-21 • Public Health Action
SETTING
Butaro Cancer Centre of Excellence (BCCOE), Burera District, Rwanda.

OBJECTIVES
To describe characteristics, management and 6-month outcome of adult patients pre...