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Showing 1 - 20 of 47 Items
Showing 1 - 20 of 47 Items
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Research

Mycoplasma genitalium infection in Eswatini amid syndromic case management: Prevalence, coinfections, diagnostic challenges and treatment gaps

Kerschberger B, Lekelem S, Daka M, Ntshalintshali N, Mabhena E,  et al.
2025-04-17 • BMC Infectious Diseases
2025-04-17 • BMC Infectious Diseases

BACKGROUND

The global epidemic of Mycoplasma genitalium (MG) is marked by its widespread prevalence, varied resistance patterns, and significant impact on sexua...

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Clinical utility of the FilmArray® meningitis/encephalitis panel in children with suspected central nervous system infection in a low-resource setting – a prospective study in southwestern Uganda

Rasti R, Kumbakumba E, Nanjebe D, Mlotshwa P, Nassejje M,  et al.
2025-03-22 • BMC Infectious Diseases
2025-03-22 • BMC Infectious Diseases

BACKGROUND

In low-resource settings, limited laboratory capacity adds to the burden of central nervous system (CNS) infections in children and spurs overuse of ...

Conflict-associated wounds and burns infected with GLASS pathogens in the Eastern Mediterranean Region: A systematic review

Wild A, Shortall C, Dewachi O, Naim C, Green A,  et al.
2025-02-07 • BMC Infectious Diseases
2025-02-07 • BMC Infectious Diseases

BACKGROUND

While the relationship between conflict-associated injuries and antimicrobial resistance is increasingly being elucidated, data concerning civilian c...

Usability and acceptability of self-testing for hepatitis C virus exposure in a high-prevalence urban informal settlement in Karachi, Pakistan

Mazzilli S, Aslam MK, Akhtar J, Miazek M, Wailly Y,  et al.
2024-09-27 • BMC Infectious Diseases
2024-09-27 • BMC Infectious Diseases

BACKGROUND

Hepatitis C virus (HCV) antibody self-testing (HCVST) may help expand screening access and support HCV elimination efforts. Despite potential benefit...

Prevalence and factors associated with transfusion-transmissible infections among blood donors in Arua regional blood bank, Uganda

Cwinyaai N, Opio D, Kajumbula H, Zalwango JF, Akunzirwe R,  et al.
2024-09-06 • BMC Infectious Diseases
2024-09-06 • BMC Infectious Diseases

BACKGROUND

Blood transfusion services play a key role in modern healthcare delivery. In 2022, approximately 118.5 million blood donations were collected globall...

Understanding the role of video direct observed therapy for patients on an oral short-course regimen for multi-drug resistant tuberculosis: findings from a qualitative study in Eswatini

Mukooza E, Schausberger B, Mmema N, Dlamini V, Aung A,  et al.
2024-08-15 • BMC Infectious Diseases
2024-08-15 • BMC Infectious Diseases

BACKGROUND

Improving treatment success rates among multi drug-resistant tuberculosis (MDR-TB) patients is critical to reducing its incidence and mortality, but adherence poses a...

Individual and household risk factors for Ebola disease among household contacts in Mubende and Kassanda districts, Uganda, 2022

Migamba S, Ardiet DL, Migisha R, Nansikombi HT, Agaba B,  et al.
2024-03-30 • BMC Infectious Diseases
2024-03-30 • BMC Infectious Diseases
BACKGROUND
In 2022, a Sudan virus disease (SVD) outbreak occurred in Uganda, resulting in 142 confirmed cases, most in Mubende and Kassanda districts. We determined risk factors for ...

Independent clinic-based evaluation of point-of-care testing for the screening of Chlamydia trachomatis, Neisseria gonorrhoea and Trichomonas vaginalis in women-at-risk in Australia, Guatemala, Morocco, and South Africa

Shephard M, Matthews S, Kularatne R, Andrewartha K, Blondeel K,  et al.
2024-03-04 • BMC Infectious Diseases
2024-03-04 • BMC Infectious Diseases
BACKGROUND
In 2018, the World Health Organization commenced a multi-country validation study of the Cepheid GeneXpert for a range of molecular-based point-of-care (POC) tests in prim...

Peripheral Neuropathy in a Diabetic Child Treated with Linezolid for Multidrug-Resistant Tuberculosis: A Case Report and Review of the Literature

Swaminathan A, du Cros PAK, Seddon JA, Mirgayosieva S, Asladdin R,  et al.
2017-06-12 • BMC Infectious Diseases
2017-06-12 • BMC Infectious Diseases
Extensively drug-resistant (XDR) tuberculosis (TB) and multidrug resistant (MDR)-TB with additional resistance to injectable agents or fluoroquinolones are challenging to treat due to la...

Potential Impact of Multiple Interventions on HIV Incidence in a Hyperendemic Region in Western Kenya: a Modelling Study

Blaizot S, Maman D, Riche B, Mukui I, Kirubi B,  et al.
2016-04-29 • BMC Infectious Diseases
2016-04-29 • BMC Infectious Diseases
Multiple prevention interventions, including early antiretroviral therapy initiation, may reduce HIV incidence in hyperendemic settings. Our aim was to predict the short-term impact of v...

A cluster randomized controlled trial of extending ART refill intervals to six-monthly for anti-retroviral adherence clubs

Wilkinson LS, Grimsrud A, Cassidy T, Orrell C, Voget J,  et al.
2019-07-30 • BMC Infectious Diseases
2019-07-30 • BMC Infectious Diseases
BACKGROUND:
The antiretroviral therapy (ART) adherence club (AC) differentiated service delivery model, where clinically stable ART patients receive their ART refills and psychosoci...

CMV retinitis in China and SE Asia: the way forward

Heiden D, Saranchuk P
2011-11-24 • BMC Infectious Diseases
2011-11-24 • BMC Infectious Diseases
AIDS-related CMV retinitis is a common clinical problem in patients with advanced HIV/AIDS in China and Southeast Asia. The disease is causing blindness, and current clinical management,...

Characteristics of human encounters and social mixing patterns relevant to infectious diseases spread by close contact: a survey in Southwest Uganda

le Polain de Waroux O, Cohuet S, Ndazima D, Kucharski AJ, Juan-Giner A,  et al.
2018-04-11 • BMC Infectious Diseases
2018-04-11 • BMC Infectious Diseases
BACKGROUND
Quantification of human interactions relevant to infectious disease transmission through social contact is central to predict disease dynamics, yet data from low-resource ...

High levels of viral repression, malnutrition and second-line ART use in adolescents living with HIV: a mixed methods study from Myanmar

Murray J, Whitehouse K, Ousley J, Bermudez E, Soe TT,  et al.
2020-03-20 • BMC Infectious Diseases
2020-03-20 • BMC Infectious Diseases
BACKGROUND:
Adolescents living with HIV/AIDS (ALHIV) are a particularly vulnerable but often overlooked group in the HIV response despite additional disease management challenges. <...

Person-centred care in practice: perspectives from a short course regimen for multi-drug resistant tuberculosis in Karakalpakstan, Uzbekistan

Horter SCB, Stringer B, Gray NSB, Parpieva N, Safaev K,  et al.
2020-09-16 • BMC Infectious Diseases
2020-09-16 • BMC Infectious Diseases
Introduction: Person-centred care, an internationally recognised priority, describes the involvement of people in their care and treatment decisions, and the consideration of their needs...

Direct microscopy versus sputum cytology analysis and bleach sedimentation for diagnosis of tuberculosis: a prospective diagnostic study

Hepple P, Nguele P, Greig J, Bonnet MMB, Sizaire V
2010-09-21 • BMC Infectious Diseases
2010-09-21 • BMC Infectious Diseases
ABSTRACT: BACKGROUND: Diagnostic options for pulmonary tuberculosis in resource-poor settings are commonly limited to smear microscopy. We investigated whether bleach concentration by se...

A case report of a child with probable drug resistant tuberculous pericarditis with a review of challenges involved in diagnosis, treatment and follow up of children with DR-TB pericarditis

Swaminathan A, du Cros PAK, Achar J, Kliescikova J, Mirgayosieva S,  et al.
2020-04-22 • BMC Infectious Diseases
2020-04-22 • BMC Infectious Diseases
Background: There are unique challenges in the diagnosis and management of multi drug resistant tuberculosis (MDR-TB) in children. It is difficult to obtain confirmatory microbiological ...

Seroprevalence and risk factors of recent infection with hepatitis E virus during an acute outbreak in an urban setting in Chad, 2017

Vernier L, Lenglet AD, Hogema B, Moussa AM, Ariti C,  et al.
2018-06-26 • BMC Infectious Diseases
2018-06-26 • BMC Infectious Diseases
From September 2016-April 2017, Am Timan, Chad, experienced a large HEV outbreak in an urban setting with a limited impact in terms of morbidity and mortality. To better understand HEV e...

Field suitability and diagnostic accuracy of the Biocentric open real-time PCR platform for plasma-based HIV viral load quantification in Swaziland

Mpala Q, Maphalala G, Uribe PAD, de la Tour R, Kalombola S,  et al.
2018-11-14 • BMC Infectious Diseases
2018-11-14 • BMC Infectious Diseases
Viral load (VL) testing is being scaled up in resource-limited settings. However, not all commercially available VL testing methods have been evaluated under field conditions. This study...

Women experience a better long-term immune recovery and a better survival on HAART in Lao People's Democratic Republic

Bastard M, Soulinphumy K, Phimmasone P, Saadani A, Ciaffi L,  et al.
2013-01-22 • BMC Infectious Diseases
2013-01-22 • BMC Infectious Diseases
BACKGROUND
In April 2003, Médecins Sans Frontières launched an HIV/AIDS programme to provide free HAART to HIV-infected patients in Laos. Although HIV prevalence is estimated as low ...