BACKGROUND While case confirmation is most of the time not necessary for case management decisions– the measles outbreak response relies on the timely biological confirmation of outb...
Oduoye MO, Fatima E, Muzammil MA, Dave T, Irfan H, et al.
2024-01-04 • Health Science Reports
2024-01-04 • Health Science Reports
BACKGROUND AND AIMS Artificial intelligence (AI) has emerged as a transformative force in laboratory medicine, promising significant advancements in healthcare delivery. This study e...
Lamrous A, Repetto EC, Depp T, Jimenez C, Chua AC, et al.
2023-05-17 • JAC-Antimicrobial Resistance
2023-05-17 • JAC-Antimicrobial Resistance
OBJECTIVES C-reactive protein (CRP) and procalcitonin (PCT) are widely used biomarkers in high-income countries. However, evidence for their use in low- and middle-income countries (...
Muehlenbachs A, de la Rosa Vazquez O, Bausch DG, Schafer IJ, Paddock C, et al.
2016-05-25 • Journal of Infectious Diseases
2016-05-25 • Journal of Infectious Diseases
Here we describe clinicopathologic features of EVD in pregnancy. One woman infected with Sudan virus in Gulu, Uganda in 2000 had a stillbirth and survived, and another woman with Bundibu...
BACKGROUND To confirm presence of Mycobacterium tuberculosis complex, some tuberculosis culture laboratories still rely on para-nitrobenzoic acid (PNB), a traditional technique that ...
2012-03-16 • Clinical Chemistry and Laboratory Medicine
2012-03-16 • Clinical Chemistry and Laboratory Medicine
In medical humanitarian assistance, the diagnosis of diseases plays a crucial role. Laboratory investigations are one of the main diagnostic tools utilized in Médecins Sans Frontières' (...
Ronat JB, Natale A, Kesteman T, Andremont A, Elamin W, et al.
2021-10-01 • Clinical Microbiology and Infection
2021-10-01 • Clinical Microbiology and Infection
BACKGROUND In low- and middle-income countries (LMICs), data related to antimicrobial resistance (AMR) are often inconsistently collected. Humanitarian, private and non-governmental ...
Low-resource settings are disproportionately burdened by infectious diseases and antimicrobial resistance. Good quality clinical bacteriology through a well functioning reference laborat...
BACKGROUND The Mini-Lab is a simplified and modular bacteriology laboratory being developed by MSF to improve access to microbiology diagnostics and antibiotic resistance surveillanc...
Bhatt NB, Barau C, Amin A, Baudin E, Meggi B, et al.
2014-03-24 • Antimicrobial Agents and Chemotherapy
2014-03-24 • Antimicrobial Agents and Chemotherapy
This is a substudy of the Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS) Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patien...
Yambasu EE, Reid AJ, Owiti P, Manzi M, Sia Murray MJ, et al.
2017-12-31 • Pan African Medical Journal
2017-12-31 • Pan African Medical Journal
INTRODUCTION Transmissible blood-borne infections are a serious threat to blood transfusion safety in West African countries; and yet blood remains a key therapeutic product in the c...
BACKGROUND Culture media are fundamental in clinical microbiology. In laboratories in low- and middle-income countries (LMICs), they are mostly prepared in-house, which is challengin...
Ombelet S, Natale A, Ronat JB, Vandenberg O, Jacobs J, et al.
2022-04-25 • PLOS One
2022-04-25 • PLOS One
Use of equipment-free, “manual” blood cultures is still widespread in low-resource settings, as requirements for implementation of automated systems are often not met. Quality of manual ...
Ardizzoni E, Mulders W, Kotrikadze T, Goginashvili L, Pangtey H, et al.
2015-12-02 • International Journal of Tuberculosis and Lung Disease
2015-12-02 • International Journal of Tuberculosis and Lung Disease
BACKGROUND Molecular techniques rapidly detect resistance to rifampicin (RMP) and isoniazid (INH), but do not eliminate the need for culture-based drug susceptibility testing (DST) a...
Ombelet S, Natale A, Ronat JB, Kesteman T, Vandenberg O, et al.
2021-12-13 • Lancet Microbe
2021-12-13 • Lancet Microbe
BACKGROUND Manual blood culture bottles (BCBs) are frequently used in low-resource settings. There are few BCB performance evaluations, especially evaluations comparing them with aut...
Ronat JB, Natale A, Rochard A, Boillot B, Hubert J, et al.
2019-05-08 • MSF Scientific Days International 2019
2019-05-08 • MSF Scientific Days International 2019
INTRODUCTION Within MSF projects, many patients we treat have invasive bacterial infections, often in settings with increasing levels of antimicrobial resistance. However these proje...
Bloodstream infections (BSI) have a substantial impact on morbidity and mortality worldwide. Despite scarcity of data from many low- and middle-income countries (LMICs), there is increas...
