Although tuberculosis (TB) is the number-one infectious disease killer and one of the top ten causes of mortality worldwide, the global response to TB remains off track. 2 The interim 2020 targets set by the World Health Organization (WHO) End TB Strategy – to reduce new TB infections by 20%, reduce TB deaths by 35%, and eliminate catastrophic costs of treatment for families – won’t be reached unless there is a dramatic increase in the pace of the global TB response